Hello Coe,
I use Holosync and recently I have started using the PL's. I don't believe there is any conflict between the two. If anything there is Holosync embedded in the PL's. I don't believe that PL's would replace Holosync though; I think they'd be a good enhancement to it. Whichever I use, I try to give it 20 minute break in between listening sessions so that I give the brain a chance to absorb and reorganize and not to go in overload.
Hope it helps.