I use the memory supercharger whether I'm photoreading or not, but I'd say between photoreading and activating, like the night after photoreading if you are waiting 24 hours inbetween, or after you activate, to remember what you activated, both, or just regularly. When you start listening, try to listen almost every night for a couple of weeks, then after that at least once a week. Use more often when you feel you really need a boost.