Hi There:
IMO I don't think you should ignore any direction. You are going to activate your best directions and where possible lessen the impact of your less favourable directions. Such as not having your bed or desk facing those directions. That is for personal space feng shui. General space feng shui, and time feng shui you will activate and cure all directions.
Remember there are many layers to the Diamond feng shui and whether something is good or bad is determined by the label we place on it.
