I'm curious as to what that would do? I use to take both 3 times daily about a year ago due to depression. It worked great and I felt more alive than ever. But through time, I started feeling down again and started listening to paraliminals. A day later, I felt even more alive than when I took the 5htp and St John Wort which took two weeks to produce effects. I'm not an expert on serotonin and its functions. Can someone explain some of this to me?