Regardless what happens in this world on a political, social, physical...etc level, all that really matters, imho, is how I handle what is going... or appears to be going on in this moment. All the conspiracy theories could be correct along with all the prophecies of doom and destruction: but ultimately none of this matters.
If my happiness depends solely on externals-- and this is what mass culture (and my body) would lead me to believe-- I am in deep trouble. But there is another way. Actually there are many other ways. As Shakespeare said, "Nothing is good or bad, only thinking makes it so." That is true responsibility.