Don't despair - my husband and I also have opposite best directions and we had our 46th anniversary last month!
Here are the general guidelines for dealing with this:
The “day qi” comes in the front door, which will be a good direction for one of you. The other person should ideally have the good “night qi” that comes from having the crown of their head pointing in a good direction when they are in bed.
If one of you is not able to get either the good day or night qi, be sure to set really clear and strong intentions for your personal activations in the Success, Health, Relationships and Growth areas. These will maximize the personal energy and help offset the fact that neither the bed nor the front door are in an ideal position for one of you.
Any time there is a challenge when working with feng shui, there is usually a way to work around or compensate for what is going on.
All the best!