I guess I'm at a loss here (and I keep flashing on "autoerotic asphyxiation" :-) ).

I've read some claiming that taking oxygen supplements (and Piracetam) supercharges the brain.

I wouldn't radically vary my oxygen intake without first taking some brain-penetrating antioxidants. Too much of the reactive O species, or too little O2 (anerobic metabolism) up there and bad things can happen.