You can activate for any length of time you desire. It depends on your purpose.

If your purpose is comprehension comparable to regular reading, then plan on spending about 1/3 the time with the material that you would spend regular reading. So, if it takes you 10 hours to read regular, spend 3 hours
activating.

You activate until it all comes together, until it gels, until you get your purpose met.

You may Super Read and Dip through the book several times during that period--or not. You will dip into different areas, based on the information you've learned (or didn't learn) from the previous pass(es).

There is no set answer. You need to play with it to see what works best for you and your purpose.

With more experience, the amount of time you need to activate can drop precipitously.

Have fun!